Thought Leader Liaison (TLL) - East Coast

Role Overview

The Thought Leader Liaison is a senior, field-based role within Karyopharm’s U.S. Commercial team, focusing on building and enhancing strategic relationships with national, regional, and emerging thought leaders throughout the Eastern U.S. This position plays a pivotal role in advancing Karyopharm’s external engagement strategies, supporting peer-to-peer educational initiatives, guiding brand and portfolio development, and generating valuable market insights mainly in multiple myeloma, hematology, and oncology domains.

Key Responsibilities

• Develop, oversee, and execute engagement strategies targeting thought leaders in the Eastern U.S., initially emphasizing relapsed/refractory multiple myeloma with plans to expand into other hematology and oncology areas.
• Establish and nurture robust relationships with key opinion leaders (KOLs), academic institutions, community oncology providers, and strategic accounts to advance brand goals and educational efforts.
• Collaborate across functions including Marketing, Sales, Market Access, Commercial Analytics, Medical Affairs, Legal, Regulatory, and Compliance to shape strategic messaging and execute field initiatives.
• Support compliant disease-state education related to pipeline products, new indications, and launch preparation aligned with approved business and regulatory standards.
• Implement a structured region-specific insight-gathering process to analyze treatment trends, competitive landscape, unmet educational needs, patient pathways, and stakeholder priorities, converting insights into actionable recommendations for commercial and medical teams.
• Work alongside regional sales leadership and field teams to identify educational gaps, optimize healthcare professional engagement, and facilitate high-impact peer-to-peer programs and speaker events.
• Represent the company at national and regional medical congresses, advisory boards, speaker engagements, and other external forums to strengthen thought leader relationships and gather market intelligence.
• Contribute to the creation and rollout of account-based promotional tactics, disease education programs, and marketing campaigns that raise awareness and support appropriate use of Karyopharm's oncology portfolio.
• Offer strategic insights from the field regarding treatment patterns, competition, patient care pathways, and educational needs across multiple myeloma, myelofibrosis, endometrial cancer, and related oncology areas.
• Support speaker bureau activities by identifying and developing speakers, collecting feedback on event effectiveness, and optimizing education collaboration with Sales and Marketing in a compliant manner.
• Demonstrate business ownership, strategic thinking, and executive presence while thriving in a dynamic, fast-evolving commercial environment.

Qualifications

• A minimum of seven years of experience within pharmaceutical, biotech, or oncology healthcare industries.
• Background in oncology sales, field leadership, clinical practice, nurse practitioner roles, thought leader engagement, speaker bureau management, or peer education.
• A proven track record managing KOL relationships and delivering strategic engagement plans in customer-facing capacities.
• Competence in collecting, synthesizing, and presenting market insights to influence commercial strategies and leadership decisions.
• Strong capability for cross-functional collaboration involving Marketing, Sales, Market Access, Medical, Analytics, and Compliance teams.
• Outstanding communication, presentation, planning, and multitasking skills covering a broad geographic territory.
• Willingness to travel about 50%, including attendance at congresses, customer and internal meetings, and regional engagements.

Preferred Credentials

• Experience in and connections within hematology/oncology preferred.
• Knowledge of multiple myeloma, myelofibrosis, endometrial cancer, or wider solid tumor oncology highly regarded.
• Experience in thought leader engagement, peer-to-peer marketing, speaker bureaus, advisory boards, launch readiness, or disease education initiatives.
• Background supporting pipeline development, pre-launch activities, market expansion, or future-indication planning through compliant education and insights.
• Proven ability to influence senior leadership and provide strategic recommendations without direct authority.
• Strong executive presence to engage with external experts and internal stakeholders effectively.
• Residence in the Eastern U.S. / East Coast region is required.

Compensation and Benefits

Karyopharm offers a competitive compensation package including base salary in the range of $220,000 to $260,000 annually, complemented by comprehensive benefits such as medical, dental, vision coverage, 401(k) plans, equity, and potential annual bonuses. Salary is influenced by location, experience, skills, education, and internal parity. The company operates with broad salary ranges reflective of market and role specialization.

Company and Product Background

Karyopharm Therapeutics is pioneering nuclear export inhibition science to create innovative therapies for cancer patients. The company’s flagship therapy, XPOVIO® (selinexor), is a first-in-class exportin 1 inhibitor approved for adults with relapsed/refractory multiple myeloma in the U.S. and over 50 other countries. The company is advancing applications for hematologic malignancies like myelofibrosis and solid tumors such as TP53 wild-type endometrial cancer, with ongoing research into next-generation compounds.

Joining Karyopharm provides an opportunity to be part of a growing biotech environment focused on breakthrough oncology treatments, where individual contributions are recognized and valued.