Staff Research Associate II - Neurodevelopmental Proteomics Research

Position Overview

The Quantitative Biosciences Institute (QBI) Krogan Lab at UCSF is inviting applications for a Staff Research Associate II to engage in collaborative, interdisciplinary research focusing on neurodevelopmental disorders and functional proteomics. Reporting to research leadership, the successful candidate will contribute to mapping protein interactions and pathways across various cell types pertinent to neurodevelopmental disorders. This role offers hands-on experience with advanced molecular biology, neuroscience, and proteomics methodologies.

Key Responsibilities

• Perform maintenance and culturing of mammalian cells, including iPSC-derived neuronal cultures and assist in protocols for neuronal differentiation.
• Conduct molecular biology and biochemical assays, including cloning, plasmid prep, PCR, Western blotting, protein tagging, immunoprecipitation, affinity purification, and proximity labeling experiments.
• Manage project-specific inventory by ordering and tracking supplies.

Required Qualifications

• Bachelor’s degree in Biology, Biochemistry, Molecular Biology, Cell Biology, Neuroscience, Chemical Biology, or related fields plus at least one year of relevant recent lab experience, or equivalent education and experience combination.
• Proficient in mammalian cell culture techniques with aseptic handling and routine cell line maintenance.
• Experience in molecular cloning, plasmid preparation, PCR, Western blotting, and protein analysis techniques.
• Skilled in preparing laboratory reagents, stock solutions, buffers, and culture media as per protocols.
• Capability of maintaining precise lab records and adhering to standardized experimental procedures.
• Knowledgeable in lab operations such as inventory management, supply ordering, equipment maintenance, and lab safety standards.
• Hands-on experience with standard laboratory instruments including centrifuges, incubators, thermocyclers, and plate readers.
• Ability to independently prioritize multiple tasks, troubleshoot routine lab procedures, and meet deadlines efficiently.
• Strong verbal and written communication skills suited for effective teamwork in interdisciplinary research environments.
• Proficiency with Microsoft Office suite: Word, Excel, and PowerPoint.

Preferred Qualifications

• Experience with CRISPR gene editing methods.
• Familiarity with diverse gene delivery systems.

About UCSF

The University of California, San Francisco (UCSF) is a premier institution dedicated exclusively to the health sciences, recognized globally for biomedical research, advanced education, and outstanding patient care. UCSF is the home of five Nobel laureates and focuses on transformative research areas including cancer, neurodegenerative diseases, aging, and stem cells.

Commitment to Diversity and Equity

UCSF values professionalism, respect, integrity, diversity, and excellence, collectively known as our PRIDE values. We promote equity in healthcare and workforce representation, fostering an inclusive, supportive environment welcoming diverse perspectives in education, research, and patient care.

Equal Opportunity Employer

UCSF is an Equal Opportunity Employer that considers all qualified candidates without discrimination based on race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, veteran status, or other protected characteristics.

Compensation

Salary and offer components are subject to institutional approvals and depend on experience and internal equity. Specific details about benefits and total compensation are provided upon application.