Postdoctoral Fellow in Ribosome Proteomics and Molecular Biology

About the Position

This full-time postdoctoral fellowship is based in Sydney, Australia, within the School of Biotechnology & Biomolecular Science at UNSW. The successful candidate will join an Australian Research Council-funded project focused on engineering the ‘super-ribosome’ to explore post-translational modifications (PTMs) of ribosomes across various species and their role in enhancing cellular protein synthesis under stress conditions.

The School houses advanced facilities including a premier Biomolecular Mass Spectrometry Facility and the Ramaciotti Centre for Genomics. The role offers a fixed-term contract of 18 months (up to June 2028) with a salary range of $113,000 to $121,000 plus 17% superannuation and annual leave loading.

Key Responsibilities

• Conduct independent or collaborative research at a high academic standard.
• Employ molecular biology, proteomic analyses, and protein translation assays to examine ribosomal PTMs.
• Investigate novel PTMs by cloning related enzymes to assess their effects on ribosome function.
• Generate scholarly outputs and disseminate results through publications, conferences, and workshops.
• Support supervision of research students and contribute to research development activities.
• Comply with UNSW’s values, code of conduct, and health and safety policies.

Candidate Requirements

• Doctoral degree in biochemistry, molecular biology, or a related discipline.
• Extensive experience in mass spectrometry techniques and proteome analysis focused on protein PTMs.
• Strong molecular biology skills with expertise in yeast (S. cerevisiae), including genome editing via homologous recombination and phenotypic screening.
• Experienced in cloning genes in E. coli, protein expression, purification, and conducting in vitro enzyme assays.
• Proficient bioinformatics skills for protein sequence and omics data analysis.
• Knowledge of assays monitoring ribosomal translation quality.
• Proven ability to conduct high-quality independent academic research with a record of relevant publications and presentations.
• Collaborative team player with excellent interpersonal and communication skills across diverse stakeholder groups.
• Awareness of and commitment to health and safety responsibilities.

Diversity & Inclusion

UNSW is committed to equality, diversity, and inclusion in recruitment and employment practices. Candidates from diverse backgrounds are strongly encouraged to apply. Support and flexible working arrangements are available to accommodate various needs.