Director/Senior Director of Project Management

About Dianthus Therapeutics, Inc.

Dianthus Therapeutics is advancing innovative treatments for patients suffering from severe autoimmune disorders. Their lead therapeutic candidate, claseprubart (DNTH103), is engineered for extended half-life, heightened potency, and selective targeting of the active C1s complement protein responsible for disease progression. This design enables less frequent, convenient self-administered subcutaneous injections. Their second candidate, DNTH212, is a pioneering bifunctional inhibitor targeting complementary mechanisms — Type 1 IFN suppression and B cell modulation — potentially improving clinical outcomes with patient-friendly injection methods.

Role Overview

The Director or Senior Director of Program Management will oversee and monitor interdisciplinary drug development initiatives led by Dianthus' internal teams and external partners. This leader collaborates closely with scientific executives and subject-matter specialists to develop, execute, and manage strategic program plans, operational workflows, and processes to align with corporate objectives and timelines. Dianthus fosters a culture centered on core values aiming to enhance patient care, with flexibility for remote work.

Key Responsibilities

• Forge strong partnerships with scientific leadership to define overall program strategies, objectives, and work plans.
• Create and maintain integrated program plans including detailed timelines, budgets, resource allocation, and important milestones that align with objectives.
• Implement meeting management best practices to facilitate cross-functional communication, prompt and effective decision-making, and successful program execution.
• Anticipate risks, identify gaps and resource constraints, collaborating with teams and leadership to devise and apply mitigation strategies.
• Lead detailed program budgeting efforts together with scientific staff and finance departments, ensuring financial adherence throughout program execution.
• Maintain robust relationships with scientific leads, internal departments, and external partners to keep programs on track.
• Prepare and deliver impactful presentations that distill complex topics to essential points, aiding strategic planning and decision-making.
• Contribute to standardizing processes and communications to improve efficiency within the department and across R&D teams.
• Proactively seek opportunities for organizational enhancement related to team structure, processes, and communications.

Required Qualifications & Experience

• Bachelor's degree in any field is mandatory; advanced degrees (MS, PhD, MBA) in Life Sciences are preferred.
• Minimum 9 years of program management experience within the biomedical or biopharmaceutical industry, preferably focused on biologics or antibody therapies.
• At least 8 years of clinical development experience spanning candidate selection, biological system translation through Phase 1–3 trials, assay validation, and regulatory filing preparations (IND/BLA).
• Minimum 3 years of proficiency using MS Project (Timeline Expert, Smart Sheets), MS Excel, Egnyte or equivalent file collaboration systems, PowerPoint, and MS Word.
• Excellent communication and interpersonal skills capable of establishing strong relationships with internal and external stakeholders.
• Meticulous attention to detail regarding internal and external reporting accuracy.
• Strong business insight and acumen.
• PMP® certification is advantageous.
• Preferred familiarity with US FDA, EU EMA regulations, and ICH guidelines concerning biologic therapeutic products.