Clinical Research Associate

About the Company

SpyGlass Pharma, Inc. is developing long-duration drug delivery solutions aimed at protecting and improving vision for people living with chronic eye diseases, with the goal of reducing disruption to everyday life. The company brings together specialists in ophthalmology, drug delivery, pharmaceuticals, and medical devices, and is guided by a patient-first approach: “We create for patients.” With strong clinical momentum, meaningful funding, and ongoing organizational growth, the company is advancing its lead program, SpyGlass BIM-IOL, through Phase 3 clinical development.

Role Overview

The Clinical Research Associate will be part of the Clinical Operations team and will contribute directly to the planning, execution, and oversight of clinical studies. The position is hands-on and may be tailored in scope depending on the selected candidate’s experience level. The role serves as a key link between the company and clinical sites, helping ensure trials are conducted with high quality, consistency, and compliance throughout the study lifecycle.

Work Location and Travel

This is a remote role based in the United States. The position requires frequent travel to clinical trial sites nationwide, with travel expected to be as much as 70%. Candidates must already be authorized to work in the United States and be comfortable with a schedule that involves regular domestic travel.

What You Will Do

• Perform site monitoring visits at study start-up, during routine conduct, and at close-out to confirm adherence to the protocol, GCP standards, and regulatory obligations.
• Help prepare and review critical study documentation, including informed consent forms, case report forms, and investigator brochures.
• Partner with site teams to maintain complete documentation, support timely data entry, and resolve data discrepancies or queries.
• Contribute to the identification, evaluation, and training of investigative sites.
• Keep study binders and related records accurate, current, and aligned with GCP and internal SOP requirements.
• Track study status and milestone progress to help ensure timelines and quality expectations are achieved.
• Communicate site updates and monitoring findings to the Clinical Study Manager and escalate concerns when needed.
• Assist with regulatory activities by preparing clinical trial submission materials and maintaining supporting documents.
• Coordinate with functions such as Regulatory Affairs, Quality Assurance, and Project Management to support successful study delivery.

Required Background

• A bachelor’s degree in life sciences, nursing, or another relevant field.
• At least 4 years of experience in clinical affairs within the pharmaceutical or medical device sector, with preference for experience involving drug products or drug/device combination products.
• Working knowledge of GCP, FDA and ICH requirements, and standard clinical trial monitoring methods.
• Strong planning, organization, and issue-solving capabilities.
• Clear verbal and written communication skills, along with the ability to build effective relationships with site personnel and internal stakeholders.
• Experience using Microsoft Office and electronic data capture systems.
• Willingness and ability to travel domestically up to 50% to 75% as needed.

Compensation and Benefits

• Annual base pay in the range of $90,000 to $130,000, depending on experience and qualifications.
• Eligibility for an annual bonus.
• Stock options that provide ownership participation in the company’s future growth.
• Medical, dental, and vision coverage with multiple plan options for employees and families.
• Paid time off that includes holidays, vacation, and personal leave.

Equal Opportunity and Accommodation

SpyGlass Pharma is an equal opportunity employer and participates in E-Verify. The company maintains a diverse workplace and does not discriminate in hiring, training, promotion, or other employment practices based on race, color, religion, gender, national origin, age, sexual orientation, gender identity, marital status, veteran status, disability, or any other protected characteristic. Reasonable accommodations are available for individuals with disabilities. If you need an accommodation during the application process or to perform the essential functions of the role, you may contact JOBS@SPYGLASSPHARMA.COM with your request and contact details.