Bench Scientist II, DNA Production

Role overview

A biochemistry or molecular biology professional is needed to support a DNA production and protein expression laboratory in Cambridge, Massachusetts. The position sits within a biotherapeutic expression and purification team that contributes to non-GMP transient protein lead production for research and pre-clinical needs across a broad discovery portfolio. This is a two-year contract role in a fast-paced, collaborative scientific environment.

What you will do

• Run high-throughput plasmid DNA production processes independently, including bacterial growth, plasmid isolation, and sample processing.
• Work with automated laboratory systems such as Biotage, Opentrons, and similar liquid-handling equipment, including basic troubleshooting.
• Carry out DNA quality checks through gel electrophoresis, nucleic acid measurement, purity analysis, and endotoxin testing.
• Prepare samples for next-generation sequencing and assist with initial review of sequencing outputs.
• Oversee plasmid inventory, storage, and sample traceability in electronic systems.
• Keep laboratory documentation accurate and current in an electronic lab notebook.
• Coordinate with expression and purification teams so DNA is delivered on time for downstream work.
• Help improve workflows to increase throughput, consistency, and turnaround time.
• Share status updates, priorities, and any risks to keep production schedules on track.

Skills and experience needed

• Strong hands-on background in molecular biology methods, especially plasmid prep, nucleic acid purification, and DNA quantification.
• Experience with bacterial culture systems.
• Working knowledge of DNA QC techniques and sequencing sample preparation.
• Comfort with automated or semi-automated lab instruments.
• Ability to stay organized while handling multiple tasks in a high-volume setting.
• Experience using electronic lab notebooks and sample tracking tools.
• Careful attention to detail for repetitive laboratory work.
• Clear communication and strong team collaboration skills.
• Commitment to laboratory safety and compliance.

Preferred background

• Exposure to NGS library preparation or sequencing workflows.
• Familiarity with Python for analysis or workflow automation.
• Experience working with plate-based high-throughput formats such as 96-well or 384-well systems.
• Prior use of LIMS or sample management platforms such as FreezerPro or Genedata.

Education

A bachelor’s degree in Biological Sciences, Molecular Biology, Biotechnology, Biochemistry, or another related life sciences field is required.

Additional information

This opportunity is offered by a global workforce solutions company with a large international presence and a strong growth record. The organization emphasizes leadership, collaboration, professional development, work-life balance, and inclusion. It also states that hiring decisions are based on merit and that the workplace is intended to be respectful and equitable for people of all backgrounds.

Recognition

• America’s Most Honored Businesses: Top 10%
• Fastest-Growing Staffing Firm by Staffing Industry Analysts
• Included in the INC 5000 list for eight straight years
• Top 100 by the Dallas Business Journal
• Spirit of Alliance Award from Agile1